SOD2 (4C4) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB3119-50, MB3119-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: P04179

Host: Mouse

Reactivity: Human

Applications: WB

All Applications: WB: 1/500-1/1000

Background: SOD-2 is a homotetrameric manganese enzyme (also known as MnSOD) that functions in the mitochondrion. ROS are implicated in a wide range of degenerative processes, including Alzheimer’s disease, Parkinson’s disease and ischemic heart disease. Homozygous mutant mice, which lack SOD-2, exhibit dilated cardiomyopathy, accumulation of lipid in liver and skeletal muscle, metabolic acidosis, oxidative DNA damage and respiratory chain deficiencies in heart and skeletal muscle.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of SOD2 in Hela, THP-1, A549 Ramos and K562Lysates using SOD2 antibody.

Bioworld Molecular Weight: Calculated MW: 25 kDa; Observed MW: 22 kDa

Specificity: IgG2b

Alternative Name: IPOB; IPO-B; MNSOD; MVCD6; Mn-SOD; SOD2

Immunogen: Synthetic peptide corresponding to human SOD2 protein

Conjugate: Unconjugated

Modification: Unmodified