Astro Knights is a cooperative game where your deck is never shuffled. Your goal is to defeat the Boss before it destroys your team or the homeworld you are defending.

Each round the players and the boss alternate in random order. During a player's turn, they can draw fuel, technology, and weapons from the supply, equip these weapons, and attack based on the number of slots they have and use their special ability. All four bosses in this game have their own decks and abilities, and require a different strategy to be defeated